Age at first use and later substance use disorder: Shared genetic and environmental pathways for nicotine, alcohol, and cannabis.

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Age at first use and later substance use disorder: Shared genetic and environmental pathways for nicotine, alcohol, and cannabis.

Behavioral genetic studies have provided insights into why early substance use initiation is associated with increased risk for disorder. Few genetically informative studies, however, have operationalized initiation as the timing of first use and simultaneously modeled the timing of initiation and problematic use of multiple substances. Such research can help capture the risk associated with ea...

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Genetic and environmental influences on alcohol, caffeine, cannabis, and nicotine use from early adolescence to middle adulthood.

CONTEXT While both environmental and genetic factors are important in the etiology of psychoactive substance use (PSU), we know little of how these influences differ through development. OBJECTIVE To clarify the changing role of genes and environment in PSU from early adolescence through middle adulthood. DESIGN Retrospective assessment by life history calendar, with univariate and bivariat...

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ژورنال

عنوان ژورنال: Journal of Abnormal Psychology

سال: 2016

ISSN: 1939-1846,0021-843X

DOI: 10.1037/abn0000191